Gene mapping,also called genome mapping,is the creation of a genetic map assigning DNA fragments to chromosomes.
這是英文定義,說(shuō)白了就是繪制遺傳圖譜的過(guò)程.
而mapping就是繪制圖譜的意思,還有physical mapping,就是繪制物理圖譜.
When a genome is first investigated,this map is nonexistentThe map improves with the scientific progress and is perfect when the genomic DNA sequencing of the species has been completed.During this process,and for the investigation of differences in strain,the fragments are identified by small tags..當(dāng)人類(lèi)第一次接觸某個(gè)基因組時(shí),它的圖譜是不存在的.而隨著科研的進(jìn)行與深入,當(dāng)該物種的DNA編碼已經(jīng)完全破解后,它的圖譜也就逐漸完善直至完整.在這個(gè)過(guò)程中,對(duì)生物的基因進(jìn)行鑒定,以此測(cè)定它的染色體上的特定位置,然后用圖示的方式把它表示出來(lái),就形成了基因圖譜.那大俠拜托再幫我解釋下bowtie和samtools，謝謝這兩個(gè)都是數(shù)據(jù)分析工具，我估計(jì)有點(diǎn)像數(shù)據(jù)庫(kù)操做系統(tǒng)。-----------------------------------Bowtie，為了對(duì)序列進(jìn)行數(shù)據(jù)分析，由Steven Salzberg（約翰霍普金斯大學(xué)醫(yī)學(xué)院）的研究小組開(kāi)發(fā)的基因組裝配或比對(duì)軟件---------------------------SAM (Sequence Alignment/Map) format 核苷酸序列對(duì)位排列/ 圖譜格式SAM (Sequence Alignment/Map) format is a generic format for storing large nucleotide sequence alignments.核苷酸序列對(duì)位排列/ 圖譜格式是一個(gè)為了存儲(chǔ)大型核苷酸序列排列或圖譜的通用格式。至于SAM Tools provide various utilities for manipulating alignments in the SAM format, including sorting, merging, indexing and generating alignments in a per-position format.SAM Tools這個(gè)工具就是能在SAM格式中操作序列，包括分類(lèi)，合并，索引，在一個(gè)對(duì)應(yīng)格式中生成序列。-----------------------------------這兩個(gè)都是數(shù)據(jù)分析工具，我估計(jì)有點(diǎn)像數(shù)據(jù)庫(kù)操做系統(tǒng)。-----------------------------------Bowtie，為了對(duì)序列進(jìn)行數(shù)據(jù)分析，由Steven Salzberg（約翰霍普金斯大學(xué)醫(yī)學(xué)院）的研究小組開(kāi)發(fā)的基因組裝配或比對(duì)軟件---------------------------SAM (Sequence Alignment/Map) format 核苷酸序列對(duì)位排列/ 圖譜格式SAM (Sequence Alignment/Map) format is a generic format for storing large nucleotide sequence alignments.核苷酸序列對(duì)位排列/ 圖譜格式是一個(gè)為了存儲(chǔ)大型核苷酸序列排列或圖譜的通用格式。至于SAM Tools provide various utilities for manipulating alignments in the SAM format, including sorting, merging, indexing and generating alignments in a per-position format.SAM Tools這個(gè)工具就是能在SAM格式中操作序列，包括分類(lèi)，合并，索引，在一個(gè)對(duì)應(yīng)格式中生成序列。-----------------------------------這兩個(gè)都是數(shù)據(jù)分析工具，我估計(jì)有點(diǎn)像數(shù)據(jù)庫(kù)操做系統(tǒng)。-----------------------------------百度不讓我發(fā)，，，