英語翻譯
Two hundred and fifty-five physicians reported on 1,692 drug-specific promotions.“Minimally adequate safety information” did not differ:1.7 % of promotions; range 0.9–3.0 % per site.Sales representatives provided some vs.no information on harm more often in Toulouse than in Montreal and Vancouver:61 % vs.34 %,OR = 4.0; 95 % CI 2.8–5.6,or Sacramento (39 %),OR = 2.4; 95 % CI 1.7–3.6.Serious adverse events were rarely mentioned (5–6 % of promotions in all four sites),although 45 % of promotions were for drugs with US Food and Drug Administration (FDA) “black box” warnings of serious risks.Nevertheless,physicians judged the quality of scientific information to be good or excellent in 901 (54 %) of promotions,and indicated readiness to prescribe 64 % of the time.