英語翻譯
The classⅡrelease factor,in complex with GDP ,also binds the large subunit .In prokaryotes,RF3 is the classⅡrelease factor.In eukaryotes ,eRF3 in the classⅡ release factor.After the class Ⅰand classⅡrelease factors are both bound,a glycine-glycine-glutamine,or GGQ ,motif on the class Ⅰ release factor triggers hydrolysis of the protein from tRNA in the P site.
Release of the protein from the ribosome triggers the recycling of the release factors.First,GTP is exchanged for GDP on the classⅡ release factor.This cause the classⅡ release factor to push the classⅠ release factor off the ribsome.